The study1 consisted of 84 middle aged subjects who were placed on metabolic diets randomized to supplementation with wheat bran or oat bran. Fiber was administered using 6.8 g dietary fiber per 1000 calories per day up to a maximum of 16.4 g fiber per day. Average initial cholesterol was between 207-227 mg/dL.
There was a statistically significantly greater decrease with oat bran than wheat bran in cholesterol levels, a 10.4 mg/dL (.27 mmol/L) difference: (.56 vs. .29mmol/L, p=.022). In LDL cholesterol levels, there was a 9.2 mg/dL (.24 mmol/L) difference: (.39 vs. .15mmol/L, p=.024).
There was an approximate 5% decrease in serum cholesterol in the oat bran group beyond the wheat bran group.
A 5% reduction in LDL cholesterol persistently maintained may
be associated with a 10% reduction in cardiovascular mortality.2
1. Wheat-bran and oat-bran supplements' effects on blood lipids and lipoproteins. Kashtan H, Stern H, Jenkins D, Jenkins A, Hay K, Marcon N, Minkin S, Bruce WR. Am J Clin Nutr 1992;55:976-80.
2. National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment on High Blood Cholesterol in Adults. Report of the National Cholesterol Education Program Expert Panel. Arch Intern Med 1988;148:36-9.