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Specific guide to this web site for:

 1.  Medical School
      Educators 
      in Statistics

 2.  Medical Students

 3.  Science media writers

 4.  High School & College
     Statistic Teachers

   Misadventures:

1. Harvard led MI study

2. JACC study 
   (J. of Amer. Coll.
   Cardio.)

3. NEJM cath study

4. Amer. J. of Cardio.
    review of literature

5. ALLHAT
    controversy 

6. Oat bran study

7. Pregnancy & Alcohol

8. Are Geminis really
    different?
      
9. Columbia 'Miracle' Study  
                                                 

Additional Topics:

Celebrex

Limitations of Meta-Analyses

Large Randomized Clinical Trials

Tale of Two Large
Trials

Advocate meta-analyses

Network meta-analyses

"Subsequent Developments" regarding an underpowered poorly done widely publicized study study suggesting oat bran had no significant cholesterol lowering properties.

This article concerned a small study on the effects of oat bran on cholesterol levels. This poorly interpreted study which received widespread media attention at the time may have stopped the oat bran fad prematurely, but it did not stop further research.  The documentation in the scientific literature showing the cholesterol lowering effect of dietary soluble fiber (such as oat bran) as an adjunct in lowering cholesterol is extensive.

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