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Specific guide to this web site for:

 1.  Medical School
      in Statistics

 2.  Medical Students

 3.  Science media writers

 4.  High School & College
     Statistic Teachers


1. Harvard led MI study

2. JACC study 

   (J. of Amer. Coll.

3. NEJM cath study

4. Amer. J. of Cardio.
    review of literature


Oat bran study

Pregnancy & Alcohol

Are Geminis really
9. Columbia 'Miracle' Study  

Additional Topics:


Limitations of Meta-Analyses

Large Randomized Clinical Trials

Tale of Two Large

Advocate meta-analyses

Network meta-analyses




Dan G. McNamara, M.D.
Chief Emeritus

Pediatric Cardiology Department
JACC Editorial Board Member
Baylor College of Medicine
Texas Children's Hospital

November 5, 1990

Eric Roehm, M.D., Cardiology
2300 Round Rock Ave., Suite 204
Round Rock , TX    78681

Dear Dr. Roehm:

Thank you for your letter of October 17, regarding the statistical analysis in the article by Geltman, et al, in JACC, September, 1990. I think your point is well taken.  I, for one, appreciate very much your bringing this to the attention of the editorial board.

I am certainly not as well versed in statistics as you seem to be, and thus, it is my custom in reviewing a paper in which statistical analysis is an important component of study to pass the paper along to a statistician for their review. I know that Dr. Dack commonly does this himself.

In this particular case, it does not seem, however, that one need to be an expert in statistics to understand the fallacy of the reasoning behind it. I am sure that you will hear from Dr. Dack and others on the editorial board.

Sincerely yours,

Dan G. McNamara, M.D., 

Chief Emeritus
Pediatric Cardiology Department
Baylor College of Medicine
Texas Children’s Hospital

cc:       Simon Dack, M.D.
            Journal of American College of
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            New York , NY    10017